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Shenzhen Health SwifTech
AccuGen™ High-throughput solutions
AccuGen™ High-throughput solutions -rapid identification of pathogenic microorganism and drug resistance gene.

Sequencing technologies have revolutionized our ability to decode the DNA of disease-causing bacteria and viruses. The information we learn allows public health professionals to detect pathogens sooner, including many pathogens that would previously have gone undetected.

AccuGen™is a combination of ultra-multiplex PCR and next-generation sequencing technology.

With our targeted sequencing（tNGS）solution, you can find out in less than 24 hours which pathogen a patient is infected with, by using just one sample (the range of 330 different pathogens including viruses, bacteria, fungi, and parasites).

Be checkable within24 hours

tNGS Solution

Coverage of 330 Different Pathogens

Including Viruses, Bacteria, Fungi, and Parasites

AccuGen™
Full-Process Reagents for tNGS All in one solution, and culture-free.

The co-detection feature of targeted next-generation sequencing (tNGS) for DNA and RNA allows for simultaneous identification of pathogens and their genetic variations, enhancing diagnostic accuracy and enabling quicker, more effective treatment decisions in clinical settings.

It can detect all pathogens in the sample from which DNA or RNA can be extracted, including bacteria, viruses, fungi, and parasites, as well as some gene variations related to non-infectious diseases.
It usually targets known pathogens or specific gene targets for detection, and is generally suitable for the diagnosis of common pathogens or specific diseases.
AccuGen™ can rapidly identify dozens to hundreds of known pathogenic microorganisms and their virulence and/or drug-resistance genes in a sample.

330 common pathogenic microorganisms+150 drug resistance genes

AccuGen™ Focus On Core Pathogens
AccuGen series contains the detection of 150 drug resistance genes to assist in precise medication.
roduct Name Detection Range
Glycopeptide antibiotics vanA, vanC, vanD
Fluoroquinolone antibiotics patA, patB, pmrA, QnrA1, QnrB4, qacA
Aminoglycoside antibiotics ANT(2'')-Ia, armA, AAC(2')-Ib, AAC(6')-Ib, aadA3, APH(3'')-Ib, APH(6)-Id, AAC(2')-Ic, ANT(4')-Ib, APH(3')-Ia, AAC(3)-Ib, AAC(6')-Ia
Macrolide antibiotics mphB, EreA, EreB, menA, mel, mtrC, mtrE
Chloramphenicol antibiotics catB3, Paer_catB6, catB8, Sent_cmlA, folP, cls
Penicillin antibiotics NDM-5, mecA, mtrD, TEM-1, OXA-1, OXA-7, OXA-10, OXA-23, OXA-24, OXA-55, OXA-58, OXA-66, OXA-69, OXA-198, CMY-2, KPC-2
Streptomycin antibiotics ErmF, msrA, ErmA, ErmB, mel
Tetracycline antibiotics tet(A), tet(D), tet(M), tet(Q), tet(T), tet(W), TolC, adeB, Ecol_mdfA, oqxA, oqxB, rpoB
Unlocking the Truth of Clinical Pathogen Infections Through Next Generation Sequencing.
Detection duration
Detection method Bacterial culture MALDI-TOF MS AccuGen™
Prior judgment required Yes Yes No
Positive rate Medium（25%-30%） depend on the cultured sample HIGH（>95%）
Detection duration 48-72h 50h 12h
Applicable scenario The gold standard for conventional microbiological detection rapid identification of bacteria and yeast - like fungi detection of complex infections and low - abundance pathogen
Detection method PCR Poct PCR AccuGen™
Detection range 2-6 22 330
RNA & DNA No Some Yes
Sensitivity The gold standard for conventional microbiological detection rapid identification of bacteria and yeast - like fungi detection of complex infections and low - abundance pathogen
Price Low Low Affordable
Detection range
AccuGen™
  • Comprehensive

    98% coverage of common clinical pathogens

  • High sensitivity

    Detection with high sensitivity using specific primers or probes to enrich and then sequence the nucleic acids of the target microorganism.

  • Quick

    Complete the process from sample collection to result output in 24 hours.

  • Easy to use

    The tNGS solution has been verified many cases

AccuGen™ Advanced tNGS Technology for Rapid, Accurate Pathogen Detection and Enhanced Patient Care.

AccuGen™ can significantly benefit hospitalized infected patients by providing rapid and accurate pathogen identification, which enhances diagnostic accuracy and allows for timely and appropriate treatment decisions; studies have shown that tNGS achieves a higher positivity rate (up to 90%) compared to conventional microbiological methods, reduces the time required for pathogen detection, and effectively identifies mixed infections, ultimately leading to improved clinical outcomes and potentially shorter hospital stays.

Quick：

POCT

Comprehensive：

tNGS,mNGS, Bacterial culture

Cheap：

X-ray, PCR, Hematology

Easy：

Colloidal gold antigen

Detection Process
Suitable for illumina & MGl Sequencing platform.
AccuGen™ Sample Submission Requirements.
Sample Type Sample Size Collection Tube Requirements Transportation Conditions
Alveolar lavage fluid ≥2 ml Sterile threaded tube Delivery under refrigeration: 48 hours delivery to laboratary;
on dry ice Transportation: > 48 hours delivery to laboratory.
Sputum ≥2 ml Sterile threaded tube
Cerebrospinal fluid ≥2 ml Sterile threaded tube
Nasopharyngeal swab ≥2 swabs Sterile threaded tube
Blood ≥2 ml cfDNA blood collection tube Normal temperature transportation
Blood (infant) ≥2 ml cfDNA blood collection tube
Cerebrospinal fluid (infant) ≥1 ml Sterile threaded tube Delivery under refrigeration: 48 hours delivery to laboratary;
on dry ice Transportation: > 48 hours delivery to laboratory.
Urine ≥2 ml Sterile threaded tube
Tissues ≥3 mm³ Sterile threaded tube
Hydrothorax and ascites ≥2 ml Sterile threaded tube
Abscess aspiration ≥2 ml Sterile threaded tube
Wound exudate ≥2 swabs Sterile threaded tube
Bile ≥2 ml Sterile threaded tube
Joint effusion ≥2 ml Sterile threaded tube
Aqueous humor ≥0.1 ml Sterile threaded tube
Other puncture fluids ≥1 ml Sterile threaded tube
Bone marrow ≥2 ml cfDNA blood collection tube Normal temperature transportation
Pathological section ≥5 sections Section box
Intelligent Analysis and
Report System
  • 01

    Graphical operation interface, no command-line input.

  • 02

    Professional bioinformatics expertise is not necessary.

  • 03

    There is only one click needed to go from the data to the result report.

  • 04

    The visual report output supports multi-platform data analysis.

The system comprises four major functional modules: sample management, sequencing data management, information analysis, and report generation. It offers multiple input methods and a clear, intuitive data display interface, facilitating easy tracking and tracing of samples. The analysis module incorporates authoritative databases for annotating pathogens and resistance/virulence genes. The report module provides simplified interpretation and review operations, enabling one-click report generation and significantly reducing report delivery time.